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IRON DEFICIENCY IN CANCER PATIENTS, DURING CHEMO AND RADIATION THERAPY

In people who have suffered from this serious disease, as an effect of various therapies and due to various changes in the body, anemia caused by iron loss can also occur.

Iron deficiency develops gradually, when food intake is less than the required amount (daily iron requirements are 1 mg per day for men and 2 mg for women), iron reserves in liver are reduced, iron is transported and incorporated into hemoglobin, but when reserves are spent, anemia occurs.

Iron can be lost by taking drugs, cytostatic- which have a role in destroying tumor cells, but because they are not highly selective, they also destroy healthy cells, among them bone marrow cells from which red blood cells are formed. In addition to chemotherapy, radiation therapy also reduces the number of erythrocytes, and thus, the amount of iron in them. The cause of iron deficiency in this condition can be reduced by iron absorption in the small intestine, various bleeding in cancers of the gastrointestinal tract such as gastric cancer, coughing up blood in lung cancer, blood loss due to surgery. People with kidney damage, especially people on dialysis, have an increased risk of developing anemia, because the kidneys do not produce enough erythropoietin, a hormone that affects the formation of red blood cells. Iron and erythropoietin may be lost during dialysis.

General symptoms include general weakness, fatigue, decreased appetite, pale skin and mucous membranes, hair loss, dizziness and headaches, cold extremities, rapid heartbeat.

The diagnosis of anemia is made through blood analysis, if it is discovered, it is necessary to compensate primarily iron, but also other substances necessary for the construction of erythrocytes.

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